Thimerosal Allergenicity

H.A. Backman; M.G. Baines

doi:10.65636/cjo.v50i4.6984

Auteurs-es

H.A. Backman
M.G. Baines

DOI :

https://doi.org/10.65636/cjo.v50i4.6984

Mots-clés :

allergy, thimerosal, hydrogel lens

Résumé

Les auteurs examinent Les études actuelles d'un modelé de laboratoire sur l'allergénique du thimerosal. Des études ont été effectuées par I’immunisation de lapins au thimerosal : on a retrouvé dans les sérums et les larmes des anticorps spécifiques. Les lapins ont subi un essai de provocation a I’aide de lentilles a hydrogel perfilcon A, enrobées de thimerosal lié à une protéine. Ils ont observé des réactions inflammatoires analogues à celles retrouvées chez les malades sensibilises, ce qui montre que Les protéines conjuguées au thimerosal peuvent etre a la fois immunogènes et capables de provoquer des réactions allergiques.

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